Robert Henry Richards
It has been demonstrated that the endocannabinoid system is involved in a variety of skin functions, including melanogenesis, the maintenance of redox balance in UV-exposed skin cells, barrier functions, sebaceous gland activity, wound healing, and the immune response of the skin. Cannabinoid compounds and derivatives are intriguing as potential systemic and topical treatments for a variety of inflammatory, fibrotic, and pruritic skin conditions in addition to their potential use in the treatment and prevention of skin cancer. Androgenetic alopecia, atopic and seborrhoeic dermatitis, dermatomyositis, asteatotic and atopic eczema, uraemic pruritis, scalp psoriasis, systemic sclerosis, and venous leg ulcers have all been successfully treated with cannabinoid compounds. The current body of research on cannabinoid compounds as potential treatments for skin diseases is examined in this review.
KeywordsCannabinoids; Receptors For cannabinoids; Dermatitis atopy; Dermatomyositis; Fibrosis; Inflammation; Pruritus; Psoriasis; Sclerosis systemic; Healing of wounds
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