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Statistical Model for Detecting Probability of Severity Level of Hemophilia A

AKM Raquibul Bashar*and Chris P Tsokos

Hemophilia (both A and B) is categorized based on the clotting factor (factor VIII - F8 and factor IX-F9) respectively. Clotting factor tests that is also called the ‘factor assays’are necessary in order to diagnose a bleeding disorder which is eventually named as Hemophilia. The type and severity level of this disease is very important in order to create the best treatment plan for the suffering and affected individuals. Objectives of this study are to estimate a statistical model that will predict the probability of any individuals’ severity level (Mild, Moderate, Severe, Normal) having Hemophilia A even though both type of hemophilia has total 4 levels of severity including Hemophilia B. Our focus was to predict the probability of severity level of Hemophilia A based on the Race and Inhibitor history as the risk factor to predict the severity level of the disease.