Aron*
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS) of presumed autoimmune origin which develops in a genetic susceptible individual triggered by additional environmental factors. In this review we'll provide an update of basic pathogenic concepts. In addition, we'll discuss newly evolving concepts in MS pathogenesis like pathogenic heterogeneity, importance of axonal loss and therefore the role of CD8+ T lymphocytes in tissue injury.
English 
Spanish 
Chinese 
German 
French 
Japanese 
Portuguese 
Hindi