Muhammad Asif Muneer*, Muhammad Waqas, Muhammad Mubeen, Mushtaq Ahmed, Mujahid Iqbal, Muhammad Nasir Shiraz, Muhammad Mubashir Farooq and Rabbia Manzoor
The clinical microbiology and laboratory findings in puppies naturally infected with Canine Coronavirus (CCoV) and/or Canine Parvovirus (CPV) were compared with findings in uninfected puppies. Lymphopenia was the only parameter related to CCoV infection that was statistically significant, vomiting, anorexia, lethargy, hemorrhagic fluid diarrhea, leukopenia, lymphopenia, thrombocytopenia, hypoglycemia and hypoproteinemia were correlated with CPV infection.
Canine parvovirosis is globally distributed disease of dogs, caused by canine parvovirus. This study was conducted to evaluate the sero-prevalence and their associated risk factors for canine parvovirus infection along with the changes in hematological and biochemical parameters in between seropositive and seronegative dogs. A total of 154 dogs affected from gastroenteritis were screened for this study, out of which 33 dogs were found to be affected with CPV infection. The data and risk factors were screened on SPSS by logistic regression model. The whole seroreactivity to Canine parvovirus infection was 20.77%. The associated risk factors of the disease occurrence were; age of dogs and unvaccination status of dogs. Hematological parameters of seropositive dogs showed significant changes (p<0.05) in values of total erythrocyte count, total leukocyte count , hemoglobin and packed cell volume as compared to seronegative dogs. The biochemical parameters like Alanine Transaminase (ALT), Aspartate Amino Transferees (AST) and Alkaline Phosphatase (ALP) in seropositive dogs were significantly (p<0.05) high. The study highlights that unvaccinated status, young age are found to be significant risk factors associated with the occurrence of CPV and has an effect on the hemato-biochemical parameters of dogs.
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